Uji Aktivitas Antijamur Ekstrak Etanol Herba Patikan Kebo (Euphorbia hirta L.) Terhadap Candida albicans

Helen Anjelina Simanjuntak, Hermawan Purba, Wan Yuli Anjani, Rahmiati Rahmiati, Toberni S Situmorang

Abstract


The patikan kebo plant is used to cure respiratory infections, malaria, liver, hypertension, gastrointestinal, skin diseases, accelerate wound healing, antidotes, hepatitis, rheumatism and tumors. The purpose of this study was to determine the antifungal activity of patikan kebo. The research method was carried out experimentally with the paper disc diffusion method. The antifungal activity test of each concentration (1%, 2%, 3%, 4%, ketoconazole, DMSO) had respective values (7.14 mm, 7.67 mm, 8.51 mm, 8.80 mm, 26.81 mm, 0 mm). The content of secondary metabolites in the patikan kebo plant are saponins, tannins, alkaloids, steroids/triterpenoids and flavonoids. The patikan kebo plant has medium category antifungal potential.


Keywords


Antifungi; Phytochemical screening; Euphorbia hirta; Candida albicans

Full Text:

PDF

References


Ahmad, W., Singh, S., & Kumar, S. (2017). Phytochemical screening and antimicrobial study of Euphorbia hirta extracts. J Med Plants Stud, 5(2), 183-6.

Anjelina, S. H. (2020). Antibacterial activity of ethanolic extract of kitolod (Hippobromalongiflora) leaf against Staphylococcus aureus and Salmonella typhi. Asian Journal of Pharmaceutical Research and Development, 8(1), 52-54.

Davis, W. W., & Stout, T. R. (1971). Disc plate method of microbiological antibiotic assay: II. Novel procedure offering improved accuracy. Applied microbiology, 22(4), 666-670.

Dalynn. (2014). McFarland Standard. Biological.

Badrunasar, A., & Santoso, H. B. (2016). Tumbuhan Liar Berkhasiat Obat. Lombok Barat-Nusa Tenggara Barat.

Gayathri, A., & Ramesh, K. V. (2013). Antifungal activity of Euphorbia hirta L. inflorescence extract against Aspergillus flavus-A mode of action study. International Journal of Current Microbiology and Applied Sciences, 2(4), 31-37.

Linfang, H., Shilin, C., & Meihua, Y. (2012). Euphorbia hirta (Feiyangcao): A review on its ethnopharmacology, phytochemistry and pharmacology. Journal of Medicinal Plants Research, 6(39), 5176-5185.

Hidana, R., & Fauziyyah, D. K. (2016). Daya Hambat Infusum Daun Sirsak (Annona muricata L) Terhadap Pertumbuhan Jamur Pityrosporum ovale. Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi, 15(1), 100-108.

Kumar, S., Malhotra, R., & Kumar, D. (2010). Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities. Pharmacognosy reviews, 4(7), 58.

Levinson, W. Peter, C.H. Elizabeth, A.J. Jesse, N. & Brian, S. (2018). Review of Medical Microbiology & Imunologi. Fiftheenth Edition.McGraw-Hill Education. United States.

Lutfiyanti, R., Ma'ruf, W. F., & Dewi, E. N. (2012). Aktivitas antijamur senyawa bioaktif ekstrak Gelidium latifolium terhadap Candida albicans. Jurnal Pengolahan dan Bioteknologi Hasil Perikanan, 1(1), 26-33.

Marantika, V. M., & Trimulyono, G. (2019). Aktivitas Antifungi Ekstrak Lichen Parmelia sulcata terhadap Pertumbuhan Jamur Alternaria porri. Lentera Bio Vol. 8 (3): 231, 236.

Melinda, T., Asseggaf, S. N., Mahyarudin, M., & Natalia, D. (2019). Aktivitas anti jamur ekstrak etanol daun kesum (Polygonum minus Huds.) terhadap jamur Trichophyton mentagrophytes. Majalah Kedokteran Andalas, 42(3S), 48-56.

Morello, J. A., Granato, P. A., & Mizer, H. E. (2004). Laboratory manual and workbook in microbiology. McGraw-Hill Science, Engineering & Mathematics.

Nurulita, Y., Yuharmen, Y., Nenci, N., Mellani, A. O., & Nugroho, T. T. (2020). Metabolit Sekunder Sekresi Jamur Penicillium spp. Isolat Tanah Gambut Riau sebagai Antijamur Candida albicans. Chimica et Natura Acta, 8(3), 133-143.

PiĆ³ro-Jabrucka, E., Pawelczak, A., Przybyl, J. L., Baczek, K., & Weglarz, Z. (2011). Accumulation of phenolic and sterol compounds in Euphorbia hirta (L.). Herba polonica, 57(2).

Rosalim, V. V., Asseggaf, S. N. Y. R. S., Natalia, D., & Mahyarudin, M. (2019). Aktivitas Antijamur Ekstrak Etanol Daun Kesum (Polygonum minus Huds.) Terhadap Microsporum canis. Jurnal Fitofarmaka Indonesia, 6(2), 353-359.

Setiawan, A., Setiawan, F., Juliasih, N. L. G. R., Widyastuti, W., Laila, A., Setiawan, W. A., ... & Arai, M. (2022). Fungicide Activity of Culture Extract from Kocuria palustris 19C38A1 against Fusarium oxysporum. Journal of fungi, 8(3), 280.

Shih, M. F., & Cherng, J. Y. (2012). Potential applications of Euphorbia hirta in pharmacology (pp. 165-180). Rijeka, Croatia: InTech.

Sinaga, S. R., Subakir, S., & Wahyudi, F. (2012). Uji Banding Efektivitas Perasan Jeruk Purut (Citrus Hystrix Dc) Dengan Zinc Pyrithione 1% Terhadap Pertumbuhan Pityrosporum Ovale Pada Penderita Berketombe (Doctoral dissertation, Fakultas Kedokteran).

Simanjuntak, H. A., & Butar-Butar, M. (2019). Uji Aktivittas Antifungi Ekstrak Etanol Umbi Bawang Merah (Allium Cepa L.) Terhadap Candida albicans Dan Pityrosporum Ovale. EKSAKTA: Jurnal Penelitian dan Pembelajaran MIPA, 4(2), 79.

Simanjuntak, H. A., & Rahmiati, R. (2021). Antibacterial and Antifungal Activities of Patikan Kebo (Euphorbia hirta L.) Herb Ethanol Extract. Asian Journal of Pharmaceutical Research and Development, 9(5), 6-9.

Zen, N. A. M., de Queljoe, E., & Singkoh, M. (2015). Uji bioaktivitas ekstrak Padina australis dari pesisir pantai molas Sulawesi Utara terhadap bakteri Staphylococcus epidermidis. Jurnal Pesisir dan Laut Tropis, 3(2), 34-40.




DOI: https://doi.org/10.34007/jonas.v3i3.303

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Journal of Natural Sciences

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.